A woman discovers a fiery letter to her husband, this tries to cover by saying that the letter is addressed to a friend of his, this by rumors of his incredible passion becomes popular among women even gaining in some way.
Commissioner Lohmann is already planning his holidays. An unexpected phone call calls him back to work. A member of Interpol was murdered. The head of an organisation wants to come into contact with the gangster organisation of chicago. But who is this Mysterious murders happen and all trails lead to a penitentiary. But there is Joe Como, FBI agent, who is helping commissioner...
The spirit of the evil Dr. Mabuse takes over the body of a famous professor. The professor/Dr. Mabuse then begins a new crime wave that terrorizes the city.